Product Name	Anti-DUSP22/PE-Cy5.5
Chinese Name	PE-Cy5.5标记的双特异性磷酸酶22抗体
Alias	Dual specificity protein phosphatase 22; JNK stimulatory phosphatase 1; JSP 1; JSP1; LMW DSP2; Low molecular weight dual specificity phosphatase 2; MAP kinase phosphatase x; Mitogen activated protein kinase phosphatase x; MKPX; DUS22_HUMAN.
Research Area	Cell biology  Signal transduction  Apoptosis  Cyclin  transcriptional regulatory factor  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Cow, Rabbit, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	21kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DUSP22/JSP1
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase /c-Jun N-terminal kinase (SAPK/JNK) Function: Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) (By similarity). Subunit: Monomer. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas. Post-translational modifications: Myristoylation regulates subcellular location, and is necessary for activation of JNK. Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. Contains 1 tyrosine-protein phosphatase domain. Database links: Entrez Gene: 56940 Human Entrez Gene: 105352 Mouse Entrez Gene: 361242 Rat SwissProt: Q9NRW4 Human SwissProt: Q99N11 Mouse Unigene: 29106 Human Unigene: 289646 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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