Product Name	Anti-BCL2 like 14/PE-Cy5.5
Chinese Name	PE-Cy5.5标记的Bcl2样凋亡蛋白14抗体
Alias	Apoptosis facilitator Bcl 2 like 14 protein; Apoptosis facilitator Bcl 2 like protein 14; Apoptosis regulator Bcl G; Bcl2 L 14; BCL2 like 14 (apoptosis facilitator); BCL2 like 14; BCL2L14; BCLG; B2L14_HUMAN.
Research Area	Cell biology  Apoptosis  Cell type markers
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	37kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Bcl G/BCL2 like 14 (265-301aa)
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Bcl-G is a novel pro-apoptotic member of the Bcl-2 family. The human Bcl-G gene encodes two proteins through alternative mRNA splicing, Bcl-G(L) (long) and Bcl-G(S) (short) consisting of 327 and 252 amino acids in length, respectively. Bcl-G(L) mRNA is expressed widely in adult human tissues, whereas Bcl-G(S) mRNA was found only in testis. Overexpression of Bcl-G(L) or Bcl-G(S) in cells induced apoptosis although Bcl-G(S) was far more potent than Bcl-G(L). Function: Plays a role in apoptosis. Subcellular Location: Cytoplasm. Isoform 1: Cytoplasm, cytosol. Note=Diffusely distributed throughout the cytosol. Isoform 2: Endomembrane system. Note=Predominantly localized to cytosolic organelles. Tissue Specificity: Isoform 1 is widely expressed. Isoform 2 is testis-specific. Post-translational modifications: Phosphorylated by MELK, leading to inhibit its pro-apoptotic function. Similarity: Belongs to the Bcl-2 family. Database links: UniProtKB/Swiss-Prot: Q9BZR8.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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