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Product Name Anti-NLRP9/PE-Cy5.5 Chinese Name PE-Cy5.5标记的富含亮氨酸重复结构域蛋白9抗体 Alias LRR and PYD domains-containing protein 9; NACHT; NACHT, LRR and PYD domains-containing protein 9; NALP9_HUMAN; NLRP9; Nucleotide-binding oligomerization domain protein 6; PYRIN and NACHT-containing protein 12. Research Area Cell biology immunology Apoptosis transcriptional regulatory factor Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 109kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NLRP9 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008].
Function:
Involved in inflammation (Potential).
Subcellular Location:
Cytoplasm.
Similarity:
Belongs to the NLRP family.
Contains 1 DAPIN domain.
Contains 6 LRR (leucine-rich) repeats.
Contains 1 NACHT domain.
Database links:Entrez Gene: 338321 Human
Omim: 609663 Human
SwissProt: Q7RTR0 Human
Unigene: 661568 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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