Product Name	Anti-CNTF/HRP
Chinese Name	辣根过氧化物酶标记的睫状神经营养因子抗体
Alias	Ciliary Neurotrophic Factor; CNTF; CNTF_HUMAN; HCNTF.
Research Area	Developmental biology  Neurobiology  Stem cells
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Rat, Rabbit,  (predicted: Mouse, Pig, )
Applications	ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	23kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CNTF (21-70aa)
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. In addition to the predominant monocistronic transcript originating from this locus, the gene is also transcribed as a readthrough transcript with the upstream Zfp91 gene. The resulting protein is an isoform of Zfp91 and does not include Cntf sequence. Readthrough transcription of Zfp91 and Cntf has been observed in human and mouse. Function: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. Subunit: Belongs to the CNTF family. Subcellular Location: Cytoplasm. Tissue Specificity: Nervous system. Similarity: Belongs to the CNTF family. Database links: Entrez Gene: 1270 Human Entrez Gene: 12803 Mouse Entrez Gene: 25707 Rat Omim: 118945 Human SwissProt: P26441 Human SwissProt: Q6NTB0 Human SwissProt: P51642 Mouse SwissProt: P20294 Rat Unigene: 524920 Human Unigene: 715806 Human Unigene: 290924 Mouse Unigene: 6067 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 神经Stem cellsMaker 有学者认为：睫状神经营养因子能促进运动神经轴突再生，CNTF可以阻止损伤后的运动神经元的退形性变性，目前CNTF对神经营养作用还在深入的研究中。

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