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Rabbit Anti-CD56/APC Conjugated antibody
Rabbit Anti-CD56/APC Conjugated antibody
CD56 antigen; Cell Adhesion Molecule Neural 1; MSK39; N CAM 120; N CAM 140; N CAM 180; NCAM 1; NCAM1; NCAM 120; NCAM 140; NCAM1; Neural cell adhesion molecule 1 120 kDa isoform; Neural cell adhesion molecule 1 140 kDa isoform; Neural cell adhesion molecul
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  • NO.:SL0805R-APC
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,Mouse,Rat,(predicted: Chicken,Dog,Pig,Cow,Horse,Rabbit,Guinea Pig,)
    Applications:Flow-Cyt ICC IF
    concentration:1mg/ml
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Product Name Rabbit Anti-CD56/APC Conjugated antibody
Chinese Name APC标记的神经Cell adhesion molecule1抗体
Alias CD56 antigen; Cell Adhesion Molecule Neural 1; MSK39; N CAM 120; N CAM 140; N CAM 180; NCAM 1; NCAM1; NCAM 120; NCAM 140; NCAM1; Neural cell adhesion molecule 1 120 kDa isoform; Neural cell adhesion molecule 1 140 kDa isoform; Neural cell adhesion molecule 1; NCAM1_HUMAN.  
Research Area Tumour  Neurobiology  Stem cells  Cell adhesion molecule  Cell type markers  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, )
Applications Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 92kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human CD56
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]

Function:
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.

Subcellular Location:
Isoform 1, 2,: Cell membrane; Single-pass type I membrane protein. Isoform 3, 4: Cell membrane; Lipid-anchor, GPI-anchor. Isoform 5, 6: Secreted.

Similarity:
Contains 2 fibronectin type-III domains.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.

Database links:

Entrez Gene: 4684 Human

Entrez Gene: 17967 Mouse

Entrez Gene: 24586 Rat

Omim: 116930 Human

SwissProt: P13591 Human

SwissProt: P13595 Mouse

SwissProt: P13596 Rat

Unigene: 503878 Human

Unigene: 711235 Human

Unigene: 733031 Human

Unigene: 439182 Mouse

Unigene: 4974 Mouse

Unigene: 11283 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Neuron Maker

NCAM-1, short for Neural Cell Adhesion Molecule, is primarily distributed in neural tissues, neuromuscular junctions, neuro-endocrine glands, certain endocrine glands, and most cells, tissues, and tumors derived from the neural ectoderm. NCAM-1 is mainly used in research related to tumors such as retinoblastoma, medulloblastoma, astrocytoma, and neuroblastoma.

 

   

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