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Product Name Flotillin 1 Chinese Name 脂阀结构蛋白1抗体 Alias FLOT 1; FLOT1; FLOT1_HUMAN; Flotillin-1; Flotillin1; Integral membrane component of caveolae; Reggie 2. literatures Specific References (2) | SL7798R has been referenced in 2 publications.[IF=3.989] Capomaccio S et al. Equine Adipose-Derived Mesenchymal Stromal Cells Release Extracellular Vesicles Enclosing Different Subsets of Small RNAs.Stem Cells Int. 2019 Mar 18;2019:4957806. Immunoelectron Microscopy ; Human.[IF=3.23] Matsuzaka, Yasunari, et al. "Characterization and Functional Analysis of Extracellular Vesicles and Muscle-Abundant miRNAs (miR-1, miR-133a, and miR-206) in C2C12 Myocytes and mdx Mice." PLOS ONE 11.12 (2016): e0167811. IP ; Human, Mouse.Research Area Cell biology immunology Signal transduction Cyclin Cytoskeleton Extracellular matrix Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, Rat, (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 47kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Flotillin 1: 101-200/427 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.
Function:
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.
Subunit:
Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2 (By similarity). Interacts with ECM29.
Subcellular Location:
Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Melanosome. Endosome.
Similarity:
Belongs to the band 7/mec-2 family. Flotillin subfamily.
SWISS:
O75955
Gene ID:
10211
Database links:Entrez Gene: 10211 Human
Entrez Gene: 14251 Mouse
Omim: 606998 Human
SwissProt: O75955 Human
SwissProt: O08917 Mouse
Unigene: 179986 Human
Product Picture Sample:
Brain (Mouse) Lysate at 40 ug
Brain (Rat) Lysate at 40 ug
Primary: Anti-Flotillin 1 (SL7798R) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 47 kD
Observed band size: 47 kD
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