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Rabbit Anti-Flotillin 1 antibody
Rabbit Anti-Flotillin 1 antibody
FLOT 1; FLOT1; FLOT1_HUMAN; Flotillin-1; Flotillin1; Integral membrane component of caveolae; Reggie 2.
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  • NO.:SL7798R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,Rat,(predicted: Human,Dog,Pig,Cow,Horse,Rabbit,)
    Applications:WB ELISA IHC-F IF
    concentration:1mg/ml
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Details

Product Name Flotillin 1
Chinese Name 脂阀结构蛋白1抗体
Alias FLOT 1; FLOT1; FLOT1_HUMAN; Flotillin-1; Flotillin1; Integral membrane component of caveolae; Reggie 2.  
literatures
Specific References  (2)     |     SL7798R has been referenced in 2 publications.
[IF=3.989] Capomaccio S et al. Equine Adipose-Derived Mesenchymal Stromal Cells Release Extracellular Vesicles Enclosing Different Subsets of Small RNAs.Stem Cells Int. 2019 Mar 18;2019:4957806.  Immunoelectron Microscopy ;  Human.  
[IF=3.23] Matsuzaka, Yasunari, et al. "Characterization and Functional Analysis of Extracellular Vesicles and Muscle-Abundant miRNAs (miR-1, miR-133a, and miR-206) in C2C12 Myocytes and mdx Mice." PLOS ONE 11.12 (2016): e0167811.  IP ;  Human, Mouse.  
Research Area Cell biology  immunology  Signal transduction  Cyclin  Cytoskeleton  Extracellular matrix  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 47kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Flotillin 1: 101-200/427 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.

Function:
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.

Subunit:
Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2 (By similarity). Interacts with ECM29.

Subcellular Location:
Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Melanosome. Endosome.

Similarity:
Belongs to the band 7/mec-2 family. Flotillin subfamily.

SWISS:
O75955

Gene ID:
10211

Database links:

Entrez Gene: 10211 Human

Entrez Gene: 14251 Mouse

Entrez Gene: 64665 Rat

Omim: 606998 Human

SwissProt: O75955 Human

SwissProt: O08917 Mouse

SwissProt: Q9Z1E1 Rat

Unigene: 179986 Human



Product Picture
Sample:
Brain (Mouse) Lysate at 40 ug
Brain (Rat) Lysate at 40 ug
Primary: Anti-Flotillin 1 (SL7798R) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 47 kD
Observed band size: 47 kD
Sample:
Lane 1: Mouse Heart tissue lysates
Lane 2: Rat Heart tissue lysates
Primary: Anti-Flotillin 1 (SL7798R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 47 kD
Observed band size: 47 kD

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