Product Name	SLC25A6
Chinese Name	Mitochondrion载体腺嘌呤核苷酸Transporter6抗体
Alias	Adenine nucleotide translocator 3; ADP ATP carrier protein 3; ADP ATP carrier protein isoform T2; ADP ATP carrier protein liver; ADP/ATP translocase 3; ADP/ATP translocator of liver; ANT 3; ANT3; ANT3Y; MGC17525; Solute carrier family 25 (mitochondrial carrier adenine nucleotide translocator) member 6; Solute carrier family 25 member 6; ADT3_HUMAN.
Research Area	Cell biology  Signal transduction  transcriptional regulatory factor  Mitochondrion
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,  (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Rabbit, Zebrafish, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	33kDa
Cellular localization	cytoplasmic The cell membrane Mitochondrion
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SLC25A6: 56-150/298
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	SLC25A6 (solute carrier family 25, member A6) participates in the exchange of ADP and ATP across the mitochondrial inner membrane. It may be involved in the formation of the permeability transition pore complex (PTPC), a multiprotein complex built up at the contact site between the inner and the outer mitochondrial membranes. Opening of the PTPC causes massive swelling of mitochondria, rupture of the outer membrane and release of intermembrane components that induce apoptosis. Function: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis. Subunit: Found in a complex with ARL2, ARL2BP and SLC25A6. Homodimer. Interacts with influenza A virus PB1-F2 protein and HIV-1 Vpr. Subcellular Location: Mitochondrion inner membrane; Multi-pass membrane protein. Similarity: Belongs to the mitochondrial carrier family. Contains 3 Solcar repeats. SWISS: P12236 Gene ID: 293 Database links: Entrez Gene: 293 Human Omim: 300151 Human Omim: 403000 Human SwissProt: P12236 Human Unigene: 350927 Human

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