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Product Name CTRP1 Chinese Name 补体C1qTumour坏死因子相关蛋白1抗体 Alias C1q and tumor necrosis factor related protein 1; C1QT1_HUMAN; C1QTNF1 antibody Complement C1q tumor necrosis factor related protein 1; Complement C1q tumor necrosis factor-related protein 1; CTRP 1; FLJ90694; G protein coupled receptor interacting protein 1; G protein-coupled receptor-interacting protein; GIP; ZSIG37; G protein coupled receptor interacting protein 1. Research Area Cardiovascular Signal transduction Diabetes Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 29kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CTRP1: 51-150/281 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail CTRP1 enhances the production of aldosterone. CTRP1 was highly expressed in obese subjects as well as up-regulated in hypertensive patients, CTRP1 may be a newly identified molecular link between obesity and hypertension.
Subcellular Location:
Secreted (Potential).
Similarity:
Contains 1 C1q domain.
Contains 1 collagen-like domain.
SWISS:
Q9BXJ1
Gene ID:
114897
Database links:Entrez Gene: 114897 Human
Entrez Gene: 56745 Mouse
GenBank: NP_940995 Human
Omim: 610365 Human
SwissProt: Q9BXJ1 Human
SwissProt: Q9QXP7 Mouse
Unigene: 201398 Human
Unigene: 23845 Mouse
Unigene: 53880 Rat
Unigene: 82211 Rat
补体Clq TNF相关蛋白1(complement-Clq TNF-related protein 1,CTRP1)属于CTRP超家族成员之一,能在多种组织细胞表达,包含一个 N-末端的信号肽,一个短的可变结构域,一个胶原结构域和一个C-末端的球形结构域,从而在调节物质代谢、炎症免疫、阻止血小板聚集和抗血栓等方面发挥着重要的生物学功能.
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