Product Name	RhoGAP5
Chinese Name	Rho GTP酶激活蛋白5抗体
Alias	Arhgap5; Rho GTPase activating protein 5 ARHGAP 5; ARHGAP5; RHG05_HUMAN; p190 B; p190 RhoGAP; Rho GTPase activating protein 5; RhoGAP 5; RhoGAP; RhoGAP5.
Research Area	Cell biology  Signal transduction  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	172kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human RhoGAP5: 251-350/1502
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: GTPase-activating protein for Rho family members. May play a role in the reduction of the p21rasGTPase-activating potential of RASA1/p120GAP. Subcellular Location: Cytoplasmic. Tissue Specificity: Expressed in kidney, brain, liver and lung. Similarity: Contains 4 FF domains. Contains 1 Rho-GAP domain. SWISS: Q13017 Gene ID: 394 Database links: Entrez Gene: 394 Human Entrez Gene: 11855 Mouse Entrez Gene: 299012 Rat Omim: 602680 Human SwissProt: Q13017 Human SwissProt: P97393 Mouse Unigene: 592313 Human Unigene: 20898 Rat

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