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Product Name Zinc finger protein 445 Chinese Name Zinc finger protein445抗体 Alias MGC126535; OTTHUMP00000164036; Zinc finger protein 168; Zinc finger protein 445; Zinc finger protein with KRAB and SCAN domains 15; ZKSCAN15; ZN445_HUMAN; ZNF168; ZNF445. Research Area transcriptional regulatory factor Zinc finger protein Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Cow, Rabbit, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 119kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Zinc finger protein 445: 941-1031/1031 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail ZNF445 is highly expressed in adult skeletal muscle and testis, while expressed at lower levels in small intestine, pancreas, colon, thymus, uterus and peripheral blood leukocytes. Overexpression of ZNF445 results in the activation of c-Jun and serum response element, suggesting a potential role in the MAPK signaling pathway.
Function:
May be involved in transcriptional regulation.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 14 C2H2-type zinc fingers.
Contains 1 KRAB domain.
Contains 1 SCAN box domain.
SWISS:
P59923
Gene ID:
353274
Database links:Entrez Gene: 353274 Human
Entrez Gene: 235682 Mouse
SwissProt: P59923 Human
SwissProt: Q8R2V3 Mouse
Unigene: 250481 Human
Unigene: 326477 Mouse
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