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Rabbit Anti-SNAI3 antibody
Rabbit Anti-SNAI3 antibody
MGC129606; Protein snail homolog 3; SMUC; SNAI3; SNAI3_HUMAN; Snail homolog 3 (Drosophila); SNAIL3; Zfp293; Zinc finger protein 293; Zinc finger protein SNAI3; ZNF293.
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Details

Product Name SNAI3
Chinese Name Zinc finger protein293抗体
Alias MGC129606; Protein snail homolog 3; SMUC; SNAI3; SNAI3_HUMAN; Snail homolog 3 (Drosophila); SNAIL3; Zfp293; Zinc finger protein 293; Zinc finger protein SNAI3; ZNF293.  
literatures
Specific References  (1)     |     SL7213R has been referenced in 1 publications.
[IF=4.2] Zhang, Weidong, et al. "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." Chemosphere (2017).  IHC-P ;  Mouse.  
Research Area transcriptional regulatory factor  Binding protein  Zinc finger protein  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, 
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 32kDa
Cellular localization The nucleus 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human SNAI3: 101-200/292 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail SNAI3 is a member of the SNAIL gene family, named for the Drosophila snail gene, which plays roles in mesodermal formation during embryogenesis (Katoh and Katoh, 2003 [PubMed 12579345]).[supplied by OMIM, Apr 2009]

Function:
Seems to inhibit myoblast differentiation. Transcriptional repressor of E-box-dependent transactivation of downstream myogenic bHLHs genes. Binds preferentially to the canonical E-box sequences 5'-CAGGTG-3' and 5'-CACCTG-3'.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the snail C2H2-type zinc-finger protein family.
Contains 5 C2H2-type zinc fingers.

SWISS:
Q3KNW1

Gene ID:
333929

Database links:

Entrez Gene: 333929 Human

Omim: 612741 Human

SwissProt: Q3KNW1 Human

Unigene: 499548 Human

Unigene: 673548 Human



Product Picture
Sample:
A549 Cell Lysate at 40 ug
MCF-7 Cell Lysate at 40 ug
Primary: Anti-SNAI3(SL7213R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 32 kD
Observed band size: 32 kD

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