Product Name	ZNF139/ZKSCAN1
Chinese Name	Zinc finger protein139抗体
Alias	ZKSC1_HUMAN; Zinc finger protein with KRAB and SCAN domains 1; ZKSCAN1; Zinc finger protein 139; Zinc finger protein 36; Zinc finger protein KOX18; KOX18, ZNF139, ZNF36; PHZ-37; ZSCAN33; zinc finger with KRAB and SCAN domains 1;
Research Area	transcriptional regulatory factor  Zinc finger protein  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	64kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ZNF139: 61-160/563
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The ZKSCAN1 gene encodes a transcriptional regulator of the KRAB (Kruppel-associated box) subfamily of zinc finger proteins, which contain repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links (summarized by Tommerup and Vissing, 1995 [PubMed 7557990]). Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. See ZNF91 (MIM 603971) for general information on zinc finger proteins.[supplied by OMIM, Jul 2010] Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 6 C2H2-type zinc fingers. Contains 1 KRAB domain. Contains 1 SCAN box domain. SWISS: P17029 Gene ID: 7586 Database links: Entrez Gene: 7586 Human Entrez Gene: 74570 Mouse Entrez Gene: 498160 Rat SwissProt: P17029 Human SwissProt: Q8BGS3 Mouse SwissProt: Q4KLI1 Rat Unigene: 615360 Human Unigene: 213114 Mouse Unigene: 113295 Rat
Product Picture	Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night

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