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Product Name ZNHIT1 Chinese Name Cyclin1Binding protein抗体 Alias CG1I; CGBP1; Cyclin G1 binding protein 1; p18 Hamlet; Zinc finger HIT domain containing protein 1; zinc finger, HIT type 1; ZNFN4A1; ZNHI1_HUMAN. Research Area Cell biology Apoptosis Cyclin Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Cow, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 18kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ZNHIT1/CGBP1: 21-100/154 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail ZNHIT1, Zinc finger HIT domain containing protein 1, appears to play a role in p53-mediated apoptosis induction.
Function:
Seems to play a role in p53-mediated apoptosis induction.
Subunit:
Interacts with MAPK11 and MAPK14. Component of the chromatin-remodeling SRCAP complex composed of at least SRCAP, DMAP1, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1.
Post-translational modifications:
Phosphorylated on Thr by MAPK11 or MAPK14.
Stres-induced ZNHIT1 is mainly regulated at the level of protein.
Similarity:
Belongs to the ZNHIT1 family.
Contains 1 HIT-type zinc finger.
SWISS:
O43257
Gene ID:
10467
Database links:
Entrez Gene: 10467 Human
Entrez Gene: 70103 Mouse
SwissProt: O43257 Human
SwissProt: Q8R331 Mouse
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