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Rabbit Anti-ZNHIT1 antibody
Rabbit Anti-ZNHIT1 antibody
CG1I; CGBP1; Cyclin G1 binding protein 1; p18 Hamlet; Zinc finger HIT domain containing protein 1; zinc finger, HIT type 1; ZNFN4A1; ZNHI1_HUMAN.
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  • NO.:SL7093R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Cow,Rabbit,)
    Applications:WB ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Details

Product Name ZNHIT1
Chinese Name Cyclin1Binding protein抗体
Alias CG1I; CGBP1; Cyclin G1 binding protein 1; p18 Hamlet; Zinc finger HIT domain containing protein 1; zinc finger, HIT type 1; ZNFN4A1; ZNHI1_HUMAN.  
Research Area Cell biology  Apoptosis  Cyclin  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Cow, Rabbit, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 18kDa
Cellular localization The nucleus 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human ZNHIT1/CGBP1: 21-100/154 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail ZNHIT1, Zinc finger HIT domain containing protein 1, appears to play a role in p53-mediated apoptosis induction.

Function:
Seems to play a role in p53-mediated apoptosis induction.

Subunit:
Interacts with MAPK11 and MAPK14. Component of the chromatin-remodeling SRCAP complex composed of at least SRCAP, DMAP1, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1.

Post-translational modifications:
Phosphorylated on Thr by MAPK11 or MAPK14.
Stres-induced ZNHIT1 is mainly regulated at the level of protein.

Similarity:
Belongs to the ZNHIT1 family.
Contains 1 HIT-type zinc finger.

SWISS:
O43257

Gene ID:
10467

Database links:

Entrez Gene: 514997 Cow

Entrez Gene: 10467 Human

Entrez Gene: 70103 Mouse

SwissProt: Q24JY4 Cow

SwissProt: O43257 Human

SwissProt: Q8R331 Mouse



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