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Product Name NME5 Chinese Name P53诱导Apoptosis抑制蛋白抗体 Alias Inhibitor of p53 induced apoptosis beta; IPIA beta; NDK-H 5; NDP kinase homolog 5; NM23 H5; Nm23-M5; NM23H5; Non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase); Nonmetastatic cells 5, protein expressed in; Nonmetastatic protein 23, homolog 5; Nucleoside diphosphate kinase homolog 5; RSPH23; Testis specific nm23 homolog; NDK5_HUMAN. Research Area Cell biology Stem cells Cell type markers Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 24kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NME5/IPIA beta: 81-150/212 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail NME5 does not seem to have NDK kinase activity but confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. It may play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species. NME5 is specifically expressed in testis germinal cells.
Function:
Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity).
Tissue Specificity:
Specifically expressed in testis germinal cells.
Similarity:
Belongs to the NDK family.
SWISS:
P56597
Gene ID:
8382
Database links:
UniProtKB/Swiss-Prot: P56597.1
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