Product Name	DUSP22
Chinese Name	双特异性磷酸酶22抗体
Alias	Dual specificity protein phosphatase 22; JNK stimulatory phosphatase 1; JSP 1; JSP1; LMW DSP2; Low molecular weight dual specificity phosphatase 2; MAP kinase phosphatase x; Mitogen activated protein kinase phosphatase x; MKPX; DUS22_HUMAN.
Research Area	Cell biology  Signal transduction  Apoptosis  Cyclin  transcriptional regulatory factor  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Cow, Rabbit, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	21kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DUSP22/JSP1: 13-100/184
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase /c-Jun N-terminal kinase (SAPK/JNK) Function: Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) (By similarity). Subunit: Monomer. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas. Post-translational modifications: Myristoylation regulates subcellular location, and is necessary for activation of JNK. Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. Contains 1 tyrosine-protein phosphatase domain. SWISS: Q9NRW4 Gene ID: 56940 Database links: Entrez Gene: 56940 Human Entrez Gene: 105352 Mouse Entrez Gene: 361242 Rat SwissProt: Q9NRW4 Human SwissProt: Q99N11 Mouse Unigene: 29106 Human Unigene: 289646 Mouse

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