Product Name	FAIM1
Chinese Name	FAS凋亡抑制分子1抗体
Alias	FAIM 1; FAIM; Fas apoptotic inhibitory molecule 1; Fas apoptotic inhibitory molecule; FAIM1_HUMAN.
Research Area	Cell biology  Signal transduction  Apoptosis
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	20kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human FAIM1: 1-100/179
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	FAIM1 (or Fas Apoptotic Inhibitory Molecule 1) is a recently discovered negative regulator of apoptosis. FAIM1 has no significant regions of homology to other gene products that modulate Fas killing. It plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. Overexpression of FAIM1 diminishes sensitivity to Fas mediated apoptosis of B and non B cell lines. FAIM1 is highly evolutionarily conserved and is widely expressed in murine tissues, suggesting that FAIM1 plays an important role in cellular physiology. Function: Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells (By similarity). Subcellular Location: Cytoplasm (By similarity). Similarity: Belongs to the FAIM1 family. SWISS: Q9NVQ4 Gene ID: 55179 Database links: Entrez Gene: 55179 Human Entrez Gene: 23873 Mouse Entrez Gene: 100362113 Rat Entrez Gene: 140930 Rat SwissProt: Q9NVQ4 Human SwissProt: Q9WUD8 Mouse SwissProt: Q8R5H8 Rat Unigene: 173438 Human Unigene: 74605 Mouse Unigene: 106419 Rat Unigene: 199757 Rat

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