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Product Name ELOVL5 Chinese Name 长链脂肪酸延长酶长ELOVL5抗体 Alias 3 keto acyl CoA synthase ELOVL5; 3-keto acyl-CoA synthase Elovl5; dJ483K16.1; Elongation of very long chain fatty acids like 5; Elongation of very long chain fatty acids protein 5; ELOV5_HUMAN; ELOVL 5; ELOVL family member 5; ELOVL family member 5 elongation of long chain fatty acids; ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) ; ELOVL fatty acid elongase 5; ELOVL2; elovl5; Fatty acid elongase 1; HELO1; Homolog of yeast long chain polyunsaturated fatty acid elongation enzyme 2; OTTHUMP00000017867; RP3 483K16.1. Research Area Cardiovascular Cell biology Signal transduction Diabetes Immunogen Species Rabbit Clonality Polyclonal React Species Human, Rat, (predicted: Mouse, Dog, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 33kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ELOVL5: 211-299/299 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA.
Tissue specificity: Ubiquitous. Highly expressed in the adrenal gland and testis. Weekly expressed in prostate, lung and brain.
Function:
Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA.
Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity:
Ubiquitous. Highly expressed in the adrenal gland and testis. Weakly expressed in prostate, lung and brain.
Similarity:
Belongs to the ELO family.
SWISS:
Q9NYP7
Gene ID:
60481
Database links:Entrez Gene: 60481 Human
Entrez Gene: 68801 Mouse
Omim: 611805 Human
SwissProt: Q9NYP7 Human
SwissProt: Q8BHI7 Mouse
Unigene: 725124 Human
Unigene: 430736 Mouse
Unigene: 475262 Mouse
Unigene: 212229 Rat
Product Picture Sample:
Lane 1: Rat Adrenal gland tissue lysates
Lane 2: Human Molt-4 cell lysates
Lane 3: Human HepG2 cell lysates
Lane 4: Human Jurkat cell lysates
Lane 5: Human U251 cell lysates
Primary: Anti-ELOVL5 (SL7054R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 33 kDa
Observed band size: 33 kDa
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