Product Name	PMPCB
Chinese Name	Mitochondrion导肽水解酶β抗体
Alias	Beta MPP; BetaMPP; Mitochondrial processing peptidase subunit beta; MPP11; MPPB; MPPP52; P 52; P52; Peptidase mitichondrial processing beta.
Research Area	Tumour  Cell biology  TumourCell biologyMaker  Mitochondrion
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,  (predicted: Human, Mouse, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	49kDa
Cellular localization	cytoplasmic Mitochondrion
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PMPCB: 181-280/489
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	PMPCB is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. PMPCB is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex. Function: Cleaves presequences (transit peptides) from mitochondrial protein precursors. Subunit: Heterodimer of alpha and beta subunits. Subcellular Location: Mitochondrion matrix. Similarity: Belongs to the peptidase M16 family. SWISS: O75439 Gene ID: 9512 Database links: UniProtKB/Swiss-Prot: O75439.2
Product Picture	Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-PMPCB Polyclonal Antibody, Unconjugated(SL7003R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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