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Product Name CXXC5 Chinese Name 二硫键氧化还原酶Zinc finger protein5抗体 Alias RINF; WID; CF5; CXXC finger protein 5; CXXC-type zinc finger protein 5; CXXC5; (Cys-Xaa-Xaa-Cys)5; CXXC5_HUMAN; HSPC195; Putative MAPK-activating protein PM08; Putative NF-kappa-B-activating protein 102; retinoid-inducible nuclear factor; WT1-induced Inhibitor of Dishevelled. Research Area Tumour Cell biology Signal transduction Stem cells Cyclin transcriptional regulatory factor Kinases and Phosphatases Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 24-34kDa Cellular localization The nucleus cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CXXC5: 251-322/322 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells.
Function:
May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells (By similarity). Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis.
Subunit:
Interacts with DVL1 (By similarity).
Subcellular Location:
Nucleus. Cytoplasm (By similarity). Note=Colocalizes with DVL1 in large bodies localized just outside the nuclear membrane (By similarity).
Similarity:
Contains 1 CXXC-type zinc finger.
SWISS:
Q7LFL8
Gene ID:
51523
Database links:
UniProtKB/Swiss-Prot: Q7LFL8.1
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