Product Name	NLRP10
Chinese Name	富含亮氨酸重复结构域蛋白10抗体
Alias	CLR11.1; NACHT, leucine rich repeat and PYD containing 10; NACHT, LRR and PYD domains containing protein 10; NACHT, LRR and PYD domains-containing protein 10; NAL10_HUMAN; NALP10; NLR family, pyrin domain containing 10; Nlrp10; NOD8; Nucleotide-binding oligomerization domain protein 8; Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10; PAN5; PYNOD.
Research Area	Cell biology  Apoptosis
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	75kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human NLRP10: 401-500/655
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Inhibits CASP1/caspase-1-dependent IL1B secretion and PYCARD-mediated apoptosis, but not that induced by FAS or BID. Tissue specificity: Widely expressed with highest levels in heart, brain and skeletal muscle. Function: Inhibits CASP1/caspase-1-dependent IL1B secretion and PYCARD-mediated apoptosis, but not that induced by FAS or BID. Subcellular Location: Oligomerizes. Interacts with PYCARD, CASP1 and IL1B. Tissue Specificity: Widely expressed with highest levels in heart, brain and skeletal muscle. Similarity: Belongs to the NLRP family. Contains 1 DAPIN domain. Contains 1 NACHT domain. SWISS: Q86W26 Gene ID: 338322 Database links: Entrez Gene: 338322 Human Entrez Gene: 244202 Mouse Omim: 609662 Human SwissProt: Q86W26 Human SwissProt: Q8CCN1 Mouse Unigene: 449636 Human Unigene: 37991 Mouse

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