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Product Name PDCD7 Chinese Name 凋亡相关蛋白7抗体 Alias Apoptosis-related protein ES18; ES18; HES18; MGC22015; Pdcd7; PDCD7_HUMAN; Programmed cell death 7; Programmed cell death protein 7. Research Area Cell biology Signal transduction Apoptosis Cyclin Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 55kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PDCD7: 301-400/485 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a 59 kDa protein that is associated with the U11 small nuclear ribonucleoprotein (snRNP), which is a component of the minor U12-type spliceosome responsible for catalyzing pre-mRNA splicing of U12-type introns. [provided by RefSeq, Dec 2010].
Function:
Promotes apoptosis when overexpressed (By similarity).
Subunit:
Interacts with RBM40. Component of the U11/U12 snRNPs that are part of the U12-type spliceosome.
Subcellular Location:
Nucleus (Potential).
SWISS:
Q8N8D1
Gene ID:
10081
Database links:Entrez Gene: 10081 Human
Entrez Gene: 50996 Mouse
Omim: 608138 Human
SwissProt: Q8N8D1 Human
SwissProt: Q9WTY1 Mouse
Unigene: 458596 Human
Unigene: 29193 Mouse
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