Product Name	LRRC15
Chinese Name	富含亮氨酸重复蛋白15抗体
Alias	Leucine-rich repeat-containing protein 15; LIB; LRC15_HUMAN.
literatures	Specific References  (1)     |     SL6815R has been referenced in 1 publications. [IF=6.107] Toriumi Kensuke. et al. LRRC15 Expression Indicates High Level of Stemness Regulated by TWIST1 in Mesenchymal Stem Cells. ISCIENCE. 2022 Dec 30  FCM ;  Human, Mouse.   PubMed:10.2139/ssrn.4314976
Research Area	Tumour  Neurobiology  Signal transduction  TumourCell biologyMaker  Alzheimer's
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	62kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human LRRC15: 251-350/581 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	LRRC15 may contribute to regulation of cell-matrix adhesion interactions with respect to astrocyte recruitment around senile plaques in Alzheimer's disease brain. LRRC15 is induced by EWS-WT1(+KTS) in the tumor DSRCT and may play a role in cellular invasion. Function: LRRC15 may contribute to regulation of cell-matrix adhesion interactions with respect to astrocyte recruitment around senile plaques in Alzheimer's disease brain. LRRC15 is induced by EWS-WT1(+KTS) in the tumor DSRCT and may play a role in cellular invasion. Subcellular Location: Membrane; Single-pass type I membrane protein (Potential) Tissue Specificity: Brain and placenta. Similarity: Contains 15 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. SWISS: Q8TF66 Gene ID: 131578 Database links: UniProtKB/Swiss-Prot: Q8TF66.2
Product Picture	Sample: Lane 1: Mouse Placenta tissue lysates Lane 2: Mouse Cerebrum tissue lysates Lane 3: Rat Placenta tissue lysates Lane 4: Rat Cerebrum tissue lysates Lane 5: Human U87MG cell lysates Lane 6: Human U-2 OS cell lysates Lane 7: Human HeLa cell lysates Primary: Anti-LRRC15 (SL6815R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 62 kDa Observed band size: 64 kDa

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