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Product Name Coronin 3 Chinese Name 肌动蛋白Binding protein3抗体 Alias CORO 1C; CORO1C; Coronin 1c; Coronin actin binding protein 1C; Coronin1c; Coronin3; CRNN 4; CRNN4; HCRNN 4; HCRNN4; COR1C_HUMAN. Research Area Cell biology Apoptosis Binding protein Cytoskeleton Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 53kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Coronin 3: 381-474/474 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008].
Function:
May be involved in cytokinesis, motility, and signal transduction (By similarity).
Subunit:
Binds actin.
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the WD repeat coronin family.
Contains 4 WD repeats.
SWISS:
Q9ULV4
Gene ID:
23603
Database links:
Entrez Gene: 23603 Human
Entrez Gene: 23790 Mouse
Omim: 605269 Human
SwissProt: Q9ULV4 Human
SwissProt: Q9WUM4 Mouse
Unigene: 330384 Human
Unigene: 260158 Mouse
Unigene: 45957 Rat
Product Picture Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Coronin 3) Polyclonal Antibody, Unconjugated (SL6799R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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