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Product Name TSP50 Chinese Name 睾丸特异蛋白酶样蛋白50抗体 Alias Cancer/testis antigen 20; CT 20; CT20; Testes specific protease 50; Testis specific protease like protein 50; TSP 50; TSP50_HUMAN. Tumour/睾丸抗原20 Research Area Tumour immunology Signal transduction TumourCell biologyMaker Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 39kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human TSP50: 151-250/385 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail TSP50 is a possible protease in human testes. It may function in mammalian spermatogenesis. Its linear catalytic structure is similar to many serine proteases, except for a Thr-for-Ser residual catalytic site substitution.
Function:
May be involved in proteolysis through its threonine endopeptidase activity.
Subcellular Location:
Endoplasmic reticulum (Probable). Note=May also localize to cytoplasmic membranes.
Tissue Specificity:
Testis specific. Differentially expressed in some breast cancer tissues.
Similarity:
Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain.
SWISS:
Q9UI38
Gene ID:
29122
Database links:Entrez Gene: 29122 Human
GenBank: NP_037402 Human
Omim: 607950 Human
SwissProt: Q9UI38 Human
Unigene: 120365 Human
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