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Product Name TIMM17A Chinese Name Mitochondrion内膜转位酶抗体 Alias Inner membrane preprotein translocase Tim17a; Mitochondrial import inner membrane translocase subunit Tim17-A; mitochondrial inner membrane translocase; preprotein translocase; TI17A_HUMAN; TIM17; TIM17A; TIMM17A; translocase of inner mitochondrial membrane 17 homolog A (yeast); TI17A_HUMAN. Research Area Tumour Cell biology Signal transduction TumourCell biologyMaker Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 18kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human TIMM17A: 31-80/171 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.Belongs to the Tim17/Tim22/Tim23 family.
Function:
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Subunit:
Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50. The complex interacts with the TIMM44 component of the PAM complex.
Subcellular Location:
Mitochondrion inner membrane; Multi-pass membrane protein.
Similarity:
Belongs to the Tim17/Tim22/Tim23 family.
SWISS:
Q99595
Gene ID:
10440
Database links:Entrez Gene: 10440 Human
Entrez Gene: 21854 Mouse
Omim: 605057 Human
SwissProt: Q99595 Human
SwissProt: Q9Z0V8 Mouse
Unigene: 20716 Human
Unigene: 2368 Mouse
Unigene: 22514 Rat
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