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Product Name HOXA9 Chinese Name 同源盒蛋白HOXA9抗体 Alias ABD-B; Abd-B, drosophila, homolog of; D6a9; Homeobox protein A9; Homeobox 1G; Homeobox A9; Homeobox protein Hox-1.7; Homeobox protein Hox-1G; Homeobox protein Hox-A9; Hox-1.7; Hox-1.7, mouse, homolog of; HOX1; Hox1.7; Hox1G; Hox1r5; Hoxa-9; Hoxa7; HOXA9/MSI2 fusion gene, included; HOXA9/NUP98 fusion gene, included; HXA9_HUMAN. literatures Specific References (1) | SL6667R has been referenced in 1 publications.[IF=1.39] Ma et al. High level of homeobox A9 and PBX homeobox 3 expression in gastric cancer correlates with poor prognosis. (2017) Oncol.Lett. 14:5883-5889 IHC-P ; Human.Research Area Developmental biology Stem cells transcriptional regulatory factor endothelial cells Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 26, 30kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human HOXA9: 275-272 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail HOXA9 is a transcription factor with a central role in both haemopoiesis and leukaemia. High levels of HOXA9 expression in haemopoietic cells is a characteristic feature of acute myeloid leukaemia (AML), and may be sufficient to cause this disease. Overexpression of Hoxa 9 markedly expands hematopoietic stem cells. HOXA9 expression changes dramatically with age - a uniformly low level of expression during early adulthood is replaced by a frequently very high expression in adults over sixty.
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the Abd-B homeobox family.
Contains 1 homeobox DNA-binding domain.
SWISS:
P31269
Gene ID:
3205
Database links:Entrez Gene: 3205 Human
Entrez Gene: 15405 Mouse
Omim: 142956 Human
SwissProt: P31269 Human
SwissProt: P09631 Mouse
Unigene: 659350 Human
Unigene: 4694 Mouse
Unigene: 203714 Rat
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