Product Name	SCYL1BP1
Chinese Name	SCYLBinding protein1抗体
Alias	hNTKL BP1; N terminal kinase like binding protein 1; NTKL binding protein 1; NTKL BP1; NTKLBP 1; NTKLBP1; SCY1 like 1 binding protein 1; SCYL1 binding protein 1; SCYL1 BP1; GORAB_HUMAN.
Research Area	Cell biology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	45kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SCYL1BP1: 201-300/394
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Defects in GORAB are the cause of geroderma osteodysplasticum (GO) [MIM:231070]; also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation. Subunit: Interacts with SCYL1 (By similarity). Interacts with RCHY1 and RAB6A/RAB6. Subcellular Location: Cytoplasm. Golgi apparatus. DISEASE: Defects in GORAB are the cause of geroderma osteodysplasticum (GO) [MIM:231070]; also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation. Similarity: Belongs to the GORAB family. SWISS: Q5T7V8 Gene ID: 92344 Database links: Entrez Gene: 92344 Human Entrez Gene: 98376 Mouse Entrez Gene: 304923 Rat Omim: 607983 Human SwissProt: Q5T7V8 Human SwissProt: Q8BRM2 Mouse SwissProt: B1H222 Rat Unigene: 183702 Human Unigene: 32901 Mouse Unigene: 45710 Rat
Product Picture	Sample: HepG2 Cell (Human) Lysate at 40 ug Primary: Anti-SCYL1BP1 (SL6643R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45 kD Observed band size: 55 kD

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