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Product Name fbpB Chinese Name 结核分枝杆菌Ag85B/fbpB抗体 Alias A85B_MYCTU; Diacylglycerol acyltransferase/mycolyltransferase Ag85B; C:2.3.1.122; EC:2.3.1.20; DGAT; 30 kDa extracellular protein; Acyl-CoA:diacylglycerol acyltransferase; Antigen 85 complex B (85B; Ag85B); Extracellular alpha-antigen; Fibronectin-binding protein B (Fbps B); MTCY180.32; Rv1886c; 85B; mpt59; Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) literatures Specific References (2) | SL6460R has been referenced in 2 publications.[IF=4.493] Fan Jiahui. et al. Study on the Correlation between Interleukin-27 and CXCL10 in Pulmonary Tuberculosis. J IMMUNOL RES. 2022;2022:2932837 IHC ; Human.[IF=3.647] Hu Sun. et al. Study on the relationship between CXCR3 and its ligands and tubal tuberculosis. Life Sci. 2021 May;272:119047 IHC ; Human.Research Area Cell biology immunology Bacteria and viruses Immunogen Species Rabbit Clonality Polyclonal Applications ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 31kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from Mycobacterium tuberculosis Ag85B: 115-154/325 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Antigen 85B is the most abundant protein expressed by Mycobacterium tuberculosis (about one quarter). It is a myocolyc transferase in the myc pathway and catalyses - like Ag85A and Ag85C - the transfer of the fatty acid mycolate from one trehalose monomycolate to another, resulting in trehalose dimycolate and free trehalose and helping build the cell wall.
Function:
Proteins of the antigen 85 complex are responsible for the high affinity of mycobacteria to fibronectin. Possesses a mycolyltransferase activity required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintaining cell wall integrity.
Subcellular Location:
Secreted.
Similarity:
Belongs to the mycobacterial A85 antigen family.
SWISS:
P9WQP1
Gene ID:
885785
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