Product Name	SNX27
Chinese Name	SNX27蛋白抗体
Alias	Methamphetamine responsive transcript 1; MGC126871; MGC126873; MGC20471; MRT1; MY014; RP11-98D18.12; Sorting nexin family member 27; KIAA0488; SNX27_HUMAN; Sorting nexin-27.
Research Area	Cell biology  immunology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	60kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SNX27: 351-450/541
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	SNX27 is involved in endocytic trafficking. In T lymphocytes it participates in the endocytic recycling pathway. SNX27 recruits PSCDBP and HT4R to early endosomes. Function: Involved in endocytic trafficking (By similarity). In T lymphocytes, participates in endocytic recycling pathway. Recruits PSCDBP and HT4R to early endosomes (By similarity). Subunit: Interacts with PSCDBP. Isoforms 1 and 2 directly interact with DGKZ. Isoforms 1 and 2 interact with HT4R isoform 5-HTA(A). Interacts with MCC. Subcellular Location: Cytoplasm, cytosol. Early endosome. Note=In T lymphocytes, recruited from the cytosol to sorting endosomes by phosphoinositide-3-kinase products. Tissue Specificity: Expressed in cells of hematopoietic origin (at protein level). Similarity: Belongs to the sorting nexin family. Contains 1 PDZ (DHR) domain. Contains 1 PX (phox homology) domain. Contains 1 Ras-associating domain. SWISS: Q96L92 Gene ID: 81609 Database links: Entrez Gene: 81609 Human Omim: 611541 Human SwissProt: Q96L92 Human Unigene: 192326 Human

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