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Product Name HDLBP Chinese Name 高密度LipoproteinBinding protein抗体 Alias HBP; HDL binding protein; high density lipoprotein binding protein; high density lipoprotein binding protein (vigilin); VGL; vigilin. Research Area Cardiovascular Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Horse, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 140kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human HDLBP/vigilin: 651-750/1368 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail High density lipoprotein-binding protein, HDLBP, also known as vigilin, specifically binds HDL molecules and may function in the removal of excess cellular cholesterol. It may also be involved in the regulation of the delivery of fats to cells for energy and storage as fats in the bloodstream are not readily metabolized in the absence of HDLBP.
Function:
Appears to play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol.
Subcellular Location:
Cytoplasm. Nucleus.
Similarity:
Contains 14 KH domains.
SWISS:
Q00341
Gene ID:
3069
Database links:Entrez Gene: 3069 Human
Entrez Gene: 110611 Mouse
Omim: 142695 Human
SwissProt: P81021 Chicken
SwissProt: Q00341 Human
SwissProt: Q8VDJ3 Mouse
Unigene: 471851 Human
Unigene: 732361 Human
Unigene: 30012 Mouse
Unigene: 8515 Rat
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