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Rabbit Anti-HDLBP antibody
Rabbit Anti-HDLBP antibody
HBP; HDL binding protein; high density lipoprotein binding protein; high density lipoprotein binding protein (vigilin); VGL; vigilin.
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  • NO.:SL6339R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Horse,)
    Applications:ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Details

Product Name HDLBP
Chinese Name 高密度LipoproteinBinding protein抗体
Alias HBP; HDL binding protein; high density lipoprotein binding protein; high density lipoprotein binding protein (vigilin); VGL; vigilin.  
Research Area Cardiovascular  Cell biology  Signal transduction  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Horse, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 140kDa
Cellular localization The nucleus cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human HDLBP/vigilin: 651-750/1368 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail High density lipoprotein-binding protein, HDLBP, also known as vigilin, specifically binds HDL molecules and may function in the removal of excess cellular cholesterol. It may also be involved in the regulation of the delivery of fats to cells for energy and storage as fats in the bloodstream are not readily metabolized in the absence of HDLBP.

Function:
Appears to play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol.

Subcellular Location:
Cytoplasm. Nucleus.

Similarity:
Contains 14 KH domains.

SWISS:
Q00341

Gene ID:
3069

Database links:

Entrez Gene: 3069 Human

Entrez Gene: 110611 Mouse

Entrez Gene: 64474 Rat

Omim: 142695 Human

SwissProt: P81021 Chicken

SwissProt: Q00341 Human

SwissProt: Q8VDJ3 Mouse

SwissProt: Q9Z1A6 Rat

Unigene: 471851 Human

Unigene: 732361 Human

Unigene: 30012 Mouse

Unigene: 8515 Rat



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