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Product Name GLUT10 Chinese Name 葡萄糖Transporter10抗体 Alias facilitated glucose transporter member 10; Glucose Transporter GLUT10; AA450473; Glucose transporter type 10; glut 10; GLUT10; GLUT-10; GTR10_HUMAN; MGC126706; SLC2A10; Solute carrier family 2; Solute carrier family 2, facilitated glucose transporter member 10. Research Area Cardiovascular Cell biology Signal transduction Diabetes Transporter Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, ) Applications ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 67kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GLUT10: 288-335/541 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Defects in SLC2A10 are the cause of arterial tortuosity syndrome (ATS) [MIM:208050]. ATS is an autosomal recessive disorder characterized by tortuosity and elongation of major arteries, often resulting in death at young age. Other typical features include aneurysms of large arteries and stenosis of the pulmonary artery, in association with facial features and several connective tissue manifestations such as soft skin and joint laxity. Histopathological findings include fragmentation of elastic fibers in the tunica media of large arteries.
Function:
Facilitative glucose transporter.
Subcellular Location:
Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region.
Tissue Specificity:
Widely expressed; highest levels in liver and pancreas.
Similarity:
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
SWISS:
O95528
Gene ID:
81031
Database links:
UniProtKB/Swiss-Prot: O95528.2
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