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Product Name OVCA2 Chinese Name 卵巢癌相关基因2蛋白抗体 Alias Candidate tumor suppressor in ovarian cancer 2; Candidate tumor suppressor OVCA2; ovarian cancer associated gene 2 protein; Ovarian cancer gene 2 protein; ovarian tumor suppressor candidate 2; OVCA2_HUMAN. Research Area Tumour Chromatin and nuclear signals Signal transduction transcriptional regulatory factor TumourCell biologyMaker Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 24kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human OVCA2: 11-100/227 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Ubiquitously expressed protein which belongs to the UPF0483 (OVCA2) family. Encoded in an intron of the gene DPH1/OVCA1 (same strand).
Tissue Specificity:
Ubiquitously expressed.
Post-translational modifications:
Proteolytically degraded in response to RA and 4HPR treatment in a time- and dose-dependent manner in the promyelocytic leukemia cell line HL-60.
Similarity:
Belongs to the UPF0483 (OVCA2) family.
SWISS:
Q8WZ82
Gene ID:
124641
Database links:Entrez Gene: 124641 Human
Entrez Gene: 246257 Mouse
Omim: 607896 Human
SwissProt: Q8WZ82 Human
SwissProt: Q9D7E3 Mouse
Unigene: 513856 Human
Unigene: 41496 Mouse
Product Picture Tissue/cell: Rat ovary tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-OVCA2 Polyclonal Antibody, Unconjugated(SL6298R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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