Product Name	Oncostatin M
Chinese Name	癌基因蛋白抑瘤素M抗体
Alias	ONCM_HUMAN; Oncostatin M; Oncostatin M precursor; Oncostatin-M; OSM.
Research Area	Tumour  Cardiovascular  Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	26kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Oncostatin M: 165-252/252
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor. Function: Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity). Subcellular Location: Secreted. Similarity: Belongs to the LIF/OSM family. SWISS: P13725 Gene ID: 5008 Database links: Entrez Gene: 5008 Human Entrez Gene: 18413 Mouse Entrez Gene: 289747 Rat Omim: 165095 Human SwissProt: P13725 Human SwissProt: P53347 Mouse SwissProt: Q65Z15 Rat Unigene: 248156 Human Unigene: 131422 Mouse Oncostatin M抑瘤素M。OSM和LIF，G-CSF，IL-6 ，CNTF同属于一组cell factor，是一种调节生长的cell factor。能抑制某些Tumour细胞的生长，但不影响正常细胞。由巨噬细胞和活化Tlymphocyte分泌。

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