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Product Name SULT1A1 Chinese Name 芳基磺基转移酶1抗体 Alias ST1A1_HUMAN; SULT6B1; Aryl sulfotransferase 1; HAST1/HAST2; Human aryl sulfotransferase mRNA complete cds; P PST 1; P PST; P-PST 1; Phenol sulfating phenol sulfotransferase 1; Phenol sulfotransferase 1; Phenol-sulfating phenol sulfotransferase 1; PST; ST1A1; ST1A3; STP; STP1; Sulfotransferase 1A1; Sulfotransferase family 1A phenol preferring member 1; Sulfotransferase family cytosolic 1A phenol preferring member 1; Sulfotransferase phenol preferring 1; Thermostable phenol sulfotransferase; Ts PST; Ts-PST; TSPST1. literatures Specific References (3) | SL6283R has been referenced in 3 publications.[IF=6.107] Xiao-Hu Zhao. et al. Integrative analysis reveals marker genes for intestinal mucosa barrier repairing in clinical patients. ISCIENCE. 2023 May;:106831 WB ; Human.[IF=4.667] Guillot et al. Transcript analysis of laser capture microdissected white matter astrocytes and higher phenol sulfotransferase 1A1 expression during autoimmune neuroinflammation. (2015) J.Neuroinflammation. 12:130 IHC ; Mouse.[IF=1.813] Lv Le. et al. Green Tea Polyphenols Protect against Acetaminophen-Induced Liver Injury by Regulating the Drug Metabolizing Enzymes and Transporters. Evid-Based Compl Alt. 2020;2020:2696432 WB ; Mouse.Research Area Tumour Signal transduction TumourCell biologyMaker The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 34 kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SULT1A1: 151-250/295 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Multiple alternatively spliced variants that encode two isoforms have been identified for this gene.
Function:
Catalyzes the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Is also responsible for the sulfation and activation of minoxidil. Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.
Subunit:
Homodimer.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Liver, lung, adrenal, brain, platelets and skin.
Similarity:
Belongs to the sulfotransferase 1 family.
SWISS:
P50225
Gene ID:
6817
Database links:Entrez Gene: 6817 Human
Entrez Gene: 20887 Mouse
Omim: 171150 Human
SwissProt: P50225 Human
SwissProt: P52840 Mouse
Unigene: 567342 Human
Unigene: 368982 Mouse
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