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Product Name TRIM31, Alexa Fluor 680 conjugated Chinese Name AF750标记的TRIM31抗体 Alias C6orf13; H.sapiens mRNA for RING protein; HCG1; HCGI; Ring finger protein; RNF; Tripartite motif containing protein 31; TRI31_HUMAN. Research Area Tumour Cell biology immunology Chromatin and nuclear signals Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 48kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human TRIM31: 131-230/425 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled-coil region. The protein localizes to both the cytoplasm and the nucleus. Its function has not been identified.
Function:
Regulator of Src-induced anchorage independent cell growth (By similarity). May have E3 ubiquitin-protein ligase activity.
Subunit:
Interacts with isoform p52shc of SHC1. May form oligomers.
Subcellular Location:
Cytoplasm. Mitochondrion. Note=Predominantly expressed in the cytoplasm but a fraction is associated with the mitochondria.
Tissue Specificity:
Up-regulated in gastric adenocarcinomas.
Similarity:
Belongs to the TRIM/RBCC family.
Contains 1 B box-type zinc finger.
Contains 1 RING-type zinc finger.
SWISS:
Q9BZY9
Gene ID:
11074
Database links:Entrez Gene: 11074 Human
Omim: 609316 Human
SwissProt: Q9BZY9 Human
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