Product Name	RDH11
Chinese Name	视黄醇脱氢酶11/丙型肝炎病毒核心蛋白抗体
Alias	CGI 82; RALR1; Androgen regulated short chain dehydrogenase/reductase 1; ARSDR1; HCBP12; HCV core binding protein; HCV core binding protein HCBP12; MDT1; Prostate short chain dehydrogenase/reductase 1; PSDR1; Retinal reductase 1; retinol dehydrogenase 11 (all trans/9 cis/11 cis); Retinol dehydrogenase 11; SCALD; SDR7C1; Short chain dehydrogenase/reductase family 7C, member 1; RDH11_HUMAN.
literatures	Specific References  (1)     |     SL6214R has been referenced in 1 publications. [IF=4.366] Jae Yeon Kim. et al. PEDF-Mediated Mitophagy Triggers the Visual Cycle by Enhancing Mitochondrial Functions in a H2O2-Injured Rat Model. Cells-Basel. 2021 May;10(5):1117  IHC ;  Rat.   PubMed:34066394
Research Area	Neurobiology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	35kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human RDH11: 31-130/318
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is an NADPH-dependent retinal reductase and a short-chain dehydrogenase/reductase. The encoded protein has no steroid dehydrogenase activity. Function: Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity towards 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. Subcellular Location: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Tissue Specificity: Predominantly expressed in the epithelial cells of prostate, in both basal and luminal secretory cell populations. Expressed at low levels in spleen, thymus, testis, ovary, small intestine, colon, peripherical blood leukocytes, kidney, adrenal gland and fetal liver. Not detected in prostatic fibromuscular stromal cells, endothelial cells, or infiltrating lymphocytes. Post-translational modifications: Not glycosylated. Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. SWISS: Q8TC12 Gene ID: 51109 Database links: Entrez Gene: 51109 Human Omim: 607849 Human SwissProt: Q8TC12 Human Unigene: 226007 Human Unigene: 719925 Human

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