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Rabbit Anti-RBP4 antibody
Rabbit Anti-RBP4 antibody
plasma retinol binding protein 4; Plasma retinol-binding proteinv; Plasma retinol-binding protein(1-176); prbp; PRO2222; RBP; RET4_HUMAN; Retinol binding protein 4; retinol binding protein 4 interstitial; Retinol binding protein 4 plasma.
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  • NO.:SL6182R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,(predicted: Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,)
    Applications:WB ELISA
    concentration:1mg/ml
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Details

Product Name RBP4
Chinese Name 视黄醇Binding protein4抗体
Alias plasma retinol binding protein 4; Plasma retinol-binding proteinv; Plasma retinol-binding protein(1-176); prbp; PRO2222; RBP; RET4_HUMAN; Retinol binding protein 4; retinol binding protein 4 interstitial; Retinol binding protein 4 plasma.  
literatures
Specific References  (2)     |     SL6182R has been referenced in 2 publications.
[IF=6.543] Zhou Wan. et al. The Effects of RBP4 and Vitamin D on the Proliferation and Migration of Vascular Smooth Muscle Cells via the JAK2/STAT3 Signaling Pathway. Oxid Med Cell Longev. 2022;2022:3046777  WB ;  Rat.  
[IF=0] Najmi, Nuroh, et al. "Effects of aerobic exercise and a high-carbohydrate diet on RBP4 expression in rat skeletal muscle." Advances in Biomolecular Medicine: Proceedings of the 4th BIBMC (Bandung International Biomolecular Medicine Conference) 2016 and the 2nd ACMM (ASEAN Congress on Medical Biotechnology and Molecular Biosciences), October 4-6, 2016, Bandung, West Java, Indonesia. CRC Press, 2017.  IHC-P ;  Rat.  
Research Area Cardiovascular  immunology  Diabetes  Binding protein  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
Applications WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 23kDa
Cellular localization Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human RBP4: 71-170/201 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008].

Function:
Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.

Subcellular Location:
Secreted.

DISEASE:
Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.

Similarity:
Belongs to the calycin superfamily. Lipocalin family.

SWISS:
P02753

Gene ID:
5950

Database links:

Entrez Gene: 5950 Human

Omim: 180250 Human

SwissProt: P02753 Human

Unigene: 50223 Human



Product Picture
Sample:
Lane 1: RBP4 fusion protein (SL43011P) 0.2ug
Primary: Anti-RBP4 (SL6182R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 21kDa
Observed band size: 21kDa

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