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Rabbit Anti-PRKCDBP antibody
Rabbit Anti-PRKCDBP antibody
Cavin 3; HSRBC; MGC20400; Protein kinase C delta binding protein; Sdr related gene product that binds to c kinase; Serum deprivation response factor related gene product that binds to C kinase; SRBC; PRDBP_HUMAN.
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  • NO.:SL6085R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,(predicted: Human,Rat,Dog,Pig,Cow,Horse,Rabbit,)
    Applications:WB ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Details

Product Name PRKCDBP
Chinese Name 蛋白激酶C deltaBinding protein抗体
Alias Cavin 3; HSRBC; MGC20400; Protein kinase C delta binding protein; Sdr related gene product that binds to c kinase; Serum deprivation response factor related gene product that binds to C kinase; SRBC; PRDBP_HUMAN.  
Research Area Tumour  immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 28kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human PRKCDBP: 151-250/261 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail The protein encoded by this gene was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein.

Function:
Seems to have an immune potentiation function

Subunit:
Interacts with PRKCD and with phosphatidylserine. Phosphatidylserine may form a bridge between PKC and PKC-binding partners and stabilize the binding

Tissue Specificity:
Strongly expressed in mammary and epithelial cells.

Post-translational modifications:
In vitro, phosphorylated by PRKCD.

Similarity:
Belongs to the PTRF/SDPR family.

SWISS:
Q969G5

Gene ID:
112464

Database links:

Entrez Gene: 112464 Human

Entrez Gene: 109042 Mouse

Entrez Gene: 85332 Rat

SwissProt: A4FV37 Cow

SwissProt: Q969G5 Human

SwissProt: Q91VJ2 Mouse

SwissProt: Q9Z1H9 Rat

Unigene: 434044 Human

Unigene: 3124 Mouse

Unigene: 12281 Rat



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