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Product Name PRKCDBP Chinese Name 蛋白激酶C deltaBinding protein抗体 Alias Cavin 3; HSRBC; MGC20400; Protein kinase C delta binding protein; Sdr related gene product that binds to c kinase; Serum deprivation response factor related gene product that binds to C kinase; SRBC; PRDBP_HUMAN. Research Area Tumour immunology Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 28kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PRKCDBP: 151-250/261 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein.
Function:
Seems to have an immune potentiation function
Subunit:
Interacts with PRKCD and with phosphatidylserine. Phosphatidylserine may form a bridge between PKC and PKC-binding partners and stabilize the binding
Tissue Specificity:
Strongly expressed in mammary and epithelial cells.
Post-translational modifications:
In vitro, phosphorylated by PRKCD.
Similarity:
Belongs to the PTRF/SDPR family.
SWISS:
Q969G5
Gene ID:
112464
Database links:Entrez Gene: 112464 Human
Entrez Gene: 109042 Mouse
SwissProt: Q969G5 Human
SwissProt: Q91VJ2 Mouse
Unigene: 434044 Human
Unigene: 3124 Mouse
Unigene: 12281 Rat
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