Product Name	MEP1A/Meprin alpha
Chinese Name	苯甲酸肽水解酶抗体
Alias	Endopeptidase 2; Endopeptidase-2; Mep1a; MEP1A_HUMAN; Meprin A alpha (PABA peptide hydrolase); Meprin A alpha subunit precursor; Meprin A subunit alpha; N benzoyl L tyrosyl P amino benzoic acid hydrolase alpha subunit; N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha; PABA peptide hydrolase; PPH alpha; PPHA.
literatures	Specific References  (2)     |     SL6056R has been referenced in 2 publications. [IF=6.429] Li Mingzhou. et al. Long non-coding RNA CCL14-AS suppresses invasiveness and lymph node metastasis of colorectal cancer cells by regulating MEP1A. CANCER CELL INT. 2023 Dec;23(1):1-15  WB,IHC ;  Human.   PubMed:36793075 [IF=4.848] Zhuo Lin. et al. An Inflammatory Response-Related Gene Signature Can Impact the Immune Status and Predict the Prognosis of Hepatocellular Carcinoma. Front Oncol. 2021; 11: 644416  IHC ;  Human.   PubMed:33828988
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	77kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human MEP1A: 301-400/746
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Hydrolysis of protein and peptide substrates preferentially on carboxyl side of hydrophobic residues Subunit: Homotetramer consisting of disulfide-linked alpha subunits, homooligomer consisting of disulfide-linked alpha subunit homodimers, or heterotetramer of two alpha and two beta subunits formed by non-covalent association of two disulfide-linked heterodimers (By similarity). Interacts with MBL2 through its carbohydrate moiety. This interaction may inhibit its catalytic activity (By similarity). Subcellular Location: Membrane; Single-pass type I membrane protein. Post-translational modifications: N-glycosylated; contains GlcNAc, galactose, mannose and a small amount of fucose (By similarity). Similarity: Belongs to the peptidase M12A family. Contains 1 EGF-like domain. Contains 1 MAM domain. Contains 1 MATH domain. SWISS: Q16819 Gene ID: 4224 Database links: Entrez Gene: 4224 Human Entrez Gene: 17287 Mouse Omim: 600388 Human SwissProt: Q16819 Human SwissProt: P28825 Mouse Unigene: 179704 Human Unigene: 5346 Mouse

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