Product Name	Ephrin A3
Chinese Name	酪氨酸蛋白激酶A3受体抗体
Alias	EFL 2; EFL-2; EFL2; EFN A3; EFNA 3; Efna3; EFNA3_HUMAN; EHK1 L; EHK1 ligand; EHK1-L; EHK1L; EPH related receptor tyrosine kinase ligand 3; EPH-related receptor tyrosine kinase ligand 3; Ephrin-A3; EphrinA3; EPLG 3; EPLG3; LERK 3; LERK-3; LERK3; Ligand of eph related kinase 3.
Research Area	Cell biology  immunology  Neurobiology  Signal transduction  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	24kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Ephrin A3/EFNA3: 101-200/238
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Function: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity). Subunit: Interacts with EPHA8; activates EPHA8. Subcellular Location: Cell membrane. Tissue Specificity: Expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes. Similarity: Belongs to the ephrin family. Contains 1 ephrin RBD (ephrin receptor-binding) domain. SWISS: P52797 Gene ID: 1944 Database links:     Entrez Gene: 1944 Human Entrez Gene: 13638 Mouse Entrez Gene: 170901 Rat Omim: 601381 Human SwissProt: P52797 Human SwissProt: O08545 Mouse Unigene: 516656 Human Unigene: 331159 Mouse Unigene: 214210 Rat

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