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Product Name Contactin 3 Chinese Name 脑源性免疫球蛋白超家族蛋白3抗体 Alias BIG 1; BIG-1; Contactin-3; Plasmacytoma-associated neuronal glycoprotein; Brain derived immunoglobulin superfamily protein 1; Brain-derived immunoglobulin superfamily protein 1; KIAA1496; PANG; PCS; CNTN3. Research Area Cell biology immunology Neurobiology Cell Surface Molecule TumourCell biologyMaker Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Chicken, Dog, Cow, Horse, Rabbit, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 108kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Contactin 3: 301-400/1028 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Contactins mediate cell surface interactions during nervous system development. Contactin 3 has some neurite outgrowth-promoting activity.
Function:
Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity (By similarity).
Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Specificity:
In brain, it is expressed in frontal lobe, occipital lobe, cerebellum and amygdala.
Similarity:
Belongs to the immunoglobulin superfamily. Contactin family.
Contains 4 fibronectin type-III domains.
Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
SWISS:
Q9P232
Gene ID:
5067
Database links:Entrez Gene: 5067 Human
Entrez Gene: 18488 Mouse
Omim: 601325 Human
SwissProt: Q9P232 Human
SwissProt: Q07409 Mouse
Unigene: 12723 Human
Unigene: 435479 Mouse
Unigene: 10043 Rat
Product Picture Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-Contactin 3 Polyclonal Antibody, Unconjugated(SL6033R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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