Product Name	GAS8
Chinese Name	生长停滞特异性蛋白8抗体
Alias	Growth arrest specific protein 8; GAS 11; GAS 8; GAS-8; GAS11; Growth arrest specific 11; Growth arrest specific 8; Growth arrest specific protein 11; Growth arrest specific protein 8; GAS8_HUMAN.
Research Area	Tumour  Cell biology  immunology  Signal transduction  Cytoskeleton
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	56kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GAS8: 51-150/478
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is transcribed in the opposite orientation. This gene is a putative tumor suppressor gene. Function: Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility. Subunit: Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, flagellum basal body. Golgi apparatus. Note=Associates with microtubules. Localized to the cytoplasm of round spermatids, the tails of elongating spermatids, and mature spermatid tail bundles protruding into the lumen, and in the flagellum of epididymal spermatozoa. Tissue Specificity: Expressed in the heart, skeletal muscle, pancreas and liver. Weakly or not expressed in brain, placenta, lung and kidney. Similarity: Belongs to the GAS8 family. SWISS: O95995 Gene ID: 2622 Database links: Entrez Gene: 2622 Human Entrez Gene: 104346 Mouse Entrez Gene: 361438 Rat Omim: 605178 Human SwissProt: O95995 Human SwissProt: Q60779 Mouse SwissProt: Q499U4 Rat Unigene: 431792 Human Unigene: 117265 Mouse Unigene: 209051 Rat

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