Product Name	EXTL2
Chinese Name	外生性骨疣样蛋白2抗体
Alias	Alpha 1 4 N acetylhexosaminyltransferase EXTL2; Alpha GalNAcT EXTL2; Exostoses (multiple) like 2; Exostoses multiple like 2; Exostosin like 2; EXT L2; EXT related protein 2; EXTL 2; EXTR 2; EXTR2; Glucuronyl galactosyl proteoglycan 4 alpha N acetylglucosaminyltransferase; Multiple exostoses like 2; Processed exostosin like 2; EXTL2_HUMAN.
Research Area	Tumour  immunology  Signal transduction  Cytoskeleton
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	37kDa
Cellular localization	cytoplasmic The cell membrane Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human EXTL: 5-110/330
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	EXTL2 is a glycosyltransferase required for the biosynthesis of heparan-sulfate and is responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains. Function: Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains. Subcellular Location: Endoplasmic reticulum membrane; Single-pass type II membrane protein . Processed exostosin-like 2: Secreted. Note=A soluble form is found in the serum. Tissue Specificity: Ubiquitous. Post-translational modifications: The soluble form derives from the membrane form by proteolytic processing. Similarity: Belongs to the glycosyltransferase 47 family. SWISS: Q9UBQ6 Gene ID: BC045681 Database links: Entrez Gene: 2135 Human Entrez Gene: 58193 Mouse GenBank: BC045681 Human Omim: 602411 Human SwissProt: Q9UBQ6 Human SwissProt: Q9ES89 Mouse Unigene: 357637 Human

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