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Product Name LMO4 Chinese Name 乳腺Tumour自身抗原LMO4抗体 Alias LMO 4; LMO-4; Breast tumor autoantigen; LIM domain only 4; LIM domain only protein 4; LIM domain transcription factor LMO 4; LIM domain transcription factor LMO4; LMO4_HUMAN. literatures Specific References (1) | SL5966R has been referenced in 1 publications.[IF=1.664] Zhang PF et al. MicroRNA-139 suppresses hepatocellular carcinoma cell proliferation and migration by directly targeting Topoisomerase I. ONCOLOGY LETTERS 17: 1903-1913, 2019 WB ; Human.Research Area Tumour immunology Chromatin and nuclear signals Neurobiology Signal transduction transcriptional regulatory factor Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 18kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human LMO4: 65-165/165 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a cysteine-rich protein that contains two LIM domains but lacks a DNA-binding homeodomain. The encoded protein may play a role as a transcriptional regulator or as an oncogene. [provided by RefSeq, Aug 2008]
Function:
Probable transcriptional factor.
Subunit:
Interacts strongly with LDBS. Interacts with DEAF1, CLIM1 and CLIM2. Interacts (via the LIM zinc-binding domain 1) with RBBP8. Interacts with BRAC1 (via the BRCT domains); the interaction represses BRCA1 transcriptional activity.
Subcellular Location:
Nucleus.
Similarity:
Contains 2 LIM zinc-binding domains.
SWISS:
P61968
Gene ID:
8543
Database links:Entrez Gene: 8543 Human
Entrez Gene: 16911 Mouse
SwissProt: P61968 Human
SwissProt: P61969 Mouse
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