TEL: +86 571 56623320 EMAIL: [email protected]
Product Name ETS2 Chinese Name 癌基因ETS2抗体 Alias C ets 2 protein; ETS2; ETS2_HUMAN; Oncogene ETS2; Protein C-ets-2; V ets erythroblastosis virus E26 oncogene homolog 2. Research Area Tumour Cardiovascular Cell biology immunology Chromatin and nuclear signals transcriptional regulatory factor Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 53kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ETS2: 351-450/469 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Function:
Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the ETS family.
Contains 1 ETS DNA-binding domain.
Contains 1 PNT (pointed) domain.
SWISS:
P15036
Gene ID:
2114
Database links:Entrez Gene: 2114 Human
Entrez Gene: 23872 Mouse
Omim: 164740 Human
SwissProt: P15036 Human
SwissProt: P15037 Mouse
Unigene: 644231 Human
Unigene: 290207 Mouse
Scan Wechat Qrcode