TEL: +86 571 56623320    EMAIL: [email protected]

Rabbit Anti-ANGPTL3 antibody
Rabbit Anti-ANGPTL3 antibody
ANG 5; ANG-5; ANG5; Angiopoietin 5; Angiopoietin like 3; Angiopoietin related protein 3; Angiopoietin-5; Angiopoietin-like protein 3; Angiopoietin-related protein 3; ANGL3_HUMAN; ANGPT5; FHBL2.
Total
(Vip priceV)
Regular members: $334.4
View History [Clear]

Details

Product Name ANGPTL3
Chinese Name 血管生成素样蛋白3抗体
Alias ANG 5; ANG-5; ANG5; Angiopoietin 5; Angiopoietin like 3; Angiopoietin related protein 3; Angiopoietin-5; Angiopoietin-like protein 3; Angiopoietin-related protein 3; ANGL3_HUMAN; ANGPT5; FHBL2.  
Research Area Tumour  Cardiovascular  Cell biology  immunology  Signal transduction  Growth factors and hormones  vascular endothelial cell  The new supersedes the old  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, 
Applications WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 49kDa
Cellular localization Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human ANG5/ANGPTL3: 21-120/460 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes.

Subcellular Location:
Secreted

Tissue Specificity:
Expressed principally in liver. Weakly expressed in kidney.

Similarity:
Contains 1 fibrinogen C-terminal domain.

SWISS:
Q9Y5C1

Gene ID:
27329

Database links:

Entrez Gene: 27329 Human

Entrez Gene: 30924 Mouse

Entrez Gene: 502970 Rat

Omim: 604774 Human

SwissProt: Q9Y5C1 Human

SwissProt: Q9R182 Mouse

Unigene: 209153 Human

Unigene: 28341 Mouse



Product Picture
Sample:
Hepg2(Human) Cell Lysate at 30 ug
Primary: Anti-ANGPTL3 (SL5918R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 49 kD
Observed band size: 59 kD
Sample:
Lane 1: Human HL-60 cell Lysates
Lane 2: Human HepG2 cell Lysates
Lane 3: Human 293T cell Lysates
Lane 4: Human Raji cell Lysates
Lane 5: Human MOLT4 cell Lysates
Primary: Anti-ANGPTL3 (SL5918R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 49kDa
Observed band size: 60kDa

References (0)

No References

Bought notes(bought amounts latest0)

No one bought this product
Total 0 records, divided into1 pages First Prev Next Last

User Comment(Total0User Comment Num)

  • No comment
Total 0 records, divided into1 pages First Prev Next Last
Username: Anonymous user
E-mail:
Rank:
Content:
Verification code: captcha

Call us

+86 571 56623320

Address

Room 1-315, Kongle Changqing Building, No. 160 Guangye Road,Gongshu District, Hangzhou City, Zhejiang Province, China

Join Us with

Leave a message
* To protect against spam, please pass the CAPTCHA test below.