Product Name	FGF9
Chinese Name	碱性成纤维细胞生长因子9抗体
Alias	FGF 9; FGF-9; FGF9; FGF9_HUMAN; Fibroblast growth factor 9; GAF; Glia Activating Factor; Glia-activating factor; HBFG 9; HBFG9; HBGF-9; Heparin-binding growth factor 9; MGC119914; MGC119915.
literatures	Specific References  (2)     |     SL5906R has been referenced in 2 publications. [IF=11.501]   WB ;   PubMed:33080014 [IF=1.7] Yi, Shanyong, et al. "Expression of bioactive recombinant human fibroblast growth factor 9 in oil bodies of Arabidopsis thaliana." Protein Expression and Purification (2015).  WB ;   PubMed:26276471
Research Area	Tumour  Cardiovascular  Cell biology  immunology  Neurobiology  Growth factors and hormones
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	23kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human FGF9: 81-180/208
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors. Function: Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors. Subunit: Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Subcellular Location: Secreted. Tissue Specificity: Glial cells. Post-translational modifications: Three molecular species were found (30 kDa, 29 kDa and 25 kDa), cleaved at Leu-4, Val-13 and Ser-34 respectively. The smaller ones might be products of proteolytic digestion. Furthermore, there may be a functional signal sequence in the 30 kDa species which is uncleavable in the secretion step. DISEASE: Defects in FGF9 are the cause of multiple synostoses syndrome type 3 (SYNS3) [MIM:612961]. Multiple synostoses syndrome is an autosomal dominant condition characterized by progressive joint fusions of the fingers, wrists, ankles and cervical spine, characteristic facies and progressive conductive deafness. Similarity: Belongs to the heparin-binding growth factors family. SWISS: P31371 Gene ID: 2254 Database links: Entrez Gene: 378917 Chicken Entrez Gene: 2254 Human Entrez Gene: 14180 Mouse Entrez Gene: 396717 Pig Entrez Gene: 25444 Rat Omim: 600921 Human SwissProt: P31371 Human SwissProt: P54130 Mouse SwissProt: Q95L12 Pig SwissProt: P36364 Rat Unigene: 111 Human Unigene: 8846 Mouse Unigene: 25174 Rat

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