TEL: +86 571 56623320 EMAIL: [email protected]
Product Name MGAT5 Chinese Name glycoproteinGNTVA抗体 Alias 6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; 6-N-acetylglucosaminyltransferase; Alpha 1,3(6) mannosylglycoprotein; Alpha 1,6 mannosylglycoprotein 6 beta N acetylglucosaminyltransferase; Alpha mannoside beta 1,6 N acetylglucosaminyltransferase; Alpha mannoside beta 1,6 N acetylglucosaminyltransferase; Alpha- mannoside beta-1,6-N-acetylglucosaminyltransferase; Alpha-1; alpha-1,3(6)-mannosylglycoprotein; Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase; Alpha-mannoside beta-1; alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase; Beta 1,6 N acetyl glucosaminyltransferase; beta-1,6-N-acetyl-glucosaminyltransferase; GGNT5; GlcNAc T V; GlcNAc-T V; GNT V; GNT VA; GNT-V; GNTV; GNTVA; Mannoside acetylglucosaminyltransferase 5; Mannosyl (alpha 1,6) glycoprotein beta 1,6 N acetyl glucosaminyltransferase; mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase; Mgat5; MGT5A_HUMAN; N acetylglucosaminyl transferase V; N acetylglucosaminyltransferase V mannosyl (alpha 1,6) glycoprotein; N-acetylglucosaminyl-transferase V; N-acetylglucosaminyltransferase V. literatures Specific References (1) | SL5841R has been referenced in 1 publications.[IF=3.375] Yang P et al. Adoptive transfer of polarized M2c macrophages ameliorates acute rejection in rat liver transplantation. Am J Transl Res. 2020 Jun 15;12(6):2614-2626. WB ; Rat.Research Area Tumour Cell biology immunology Signal transduction Cell adhesion molecule Cytoskeleton Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Chicken, Dog, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 85kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MGAT5: 201-300/741 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail MGAT5 is a mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, a glycosyltransferase involved in the synthesis of protein-bound and lipid-bound oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the encoded protein's activity may correlate with the progression of invasive malignancies.
Function:
Catalyzes the addition of N-acetylglucosamine in beta 1-6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides.
Subcellular Location:
Golgi apparatus membrane; Single-pass type II membrane protein.
Similarity:
Belongs to the glycosyltransferase 18 family.
SWISS:
Q09328
Gene ID:
4249
Database links:Entrez Gene: 4249 Human
Entrez Gene: 107895 Mouse
Omim: 601774 Human
SwissProt: Q09328 Human
SwissProt: Q8R4G6 Mouse
Unigene: 651869 Human
Unigene: 214682 Mouse
Unigene: 391592 Mouse
Unigene: 472488 Mouse
Unigene: 53998 Rat
Product Picture
Scan Wechat Qrcode