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Rabbit Anti-MGAT5 antibody
Rabbit Anti-MGAT5 antibody
6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; 6-N-acetylglucosaminyltransferase; Alpha 1,3(6) mannosylglycoprotein; Alpha 1,6 mannosylglycoprotein 6 beta N acetylglucosaminyltransferase; Alpha mannoside beta 1,6 N acetylglucosaminyltran
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  • NO.:SL5841R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,(predicted: Mouse,Rat,Chicken,Dog,Rabbit,)
    Applications:WB ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Details

Product Name MGAT5
Chinese Name glycoproteinGNTVA抗体
Alias 6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; 6-N-acetylglucosaminyltransferase; Alpha 1,3(6) mannosylglycoprotein; Alpha 1,6 mannosylglycoprotein 6 beta N acetylglucosaminyltransferase; Alpha mannoside beta 1,6 N acetylglucosaminyltransferase; Alpha mannoside beta 1,6 N acetylglucosaminyltransferase; Alpha- mannoside beta-1,6-N-acetylglucosaminyltransferase; Alpha-1; alpha-1,3(6)-mannosylglycoprotein; Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase; Alpha-mannoside beta-1; alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase; Beta 1,6 N acetyl glucosaminyltransferase; beta-1,6-N-acetyl-glucosaminyltransferase; GGNT5; GlcNAc T V; GlcNAc-T V; GNT V; GNT VA; GNT-V; GNTV; GNTVA; Mannoside acetylglucosaminyltransferase 5; Mannosyl (alpha 1,6) glycoprotein beta 1,6 N acetyl glucosaminyltransferase; mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase; Mgat5; MGT5A_HUMAN; N acetylglucosaminyl transferase V; N acetylglucosaminyltransferase V mannosyl (alpha 1,6) glycoprotein; N-acetylglucosaminyl-transferase V; N-acetylglucosaminyltransferase V.  
literatures
Specific References  (1)     |     SL5841R has been referenced in 1 publications.
[IF=3.375] Yang P et al. Adoptive transfer of polarized M2c macrophages ameliorates acute rejection in rat liver transplantation. Am J Transl Res. 2020 Jun 15;12(6):2614-2626.  WB ;  Rat.  
Research Area Tumour  Cell biology  immunology  Signal transduction  Cell adhesion molecule  Cytoskeleton  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human,  (predicted: Mouse, Rat, Chicken, Dog, Rabbit, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 85kDa
Cellular localization cytoplasmic The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human MGAT5: 201-300/741 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail MGAT5 is a mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, a glycosyltransferase involved in the synthesis of protein-bound and lipid-bound oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the encoded protein's activity may correlate with the progression of invasive malignancies.

Function:
Catalyzes the addition of N-acetylglucosamine in beta 1-6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides.

Subcellular Location:
Golgi apparatus membrane; Single-pass type II membrane protein.

Similarity:
Belongs to the glycosyltransferase 18 family.

SWISS:
Q09328

Gene ID:
4249

Database links:

Entrez Gene: 4249 Human

Entrez Gene: 107895 Mouse

Entrez Gene: 65271 Rat

Omim: 601774 Human

SwissProt: Q09328 Human

SwissProt: Q8R4G6 Mouse

SwissProt: Q08834 Rat

Unigene: 651869 Human

Unigene: 214682 Mouse

Unigene: 391592 Mouse

Unigene: 472488 Mouse

Unigene: 53998 Rat



Product Picture
Sample:
HepG2(Human) Cell Lysate at 30 ug
Primary: Anti- MGAT5 (SL5841R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 85 kD
Observed band size: 85 kD

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