Product Name	DCBLD2
Chinese Name	endothelial cells和平滑肌细胞衍生的神经纤毛蛋白抗体
Alias	CLCP1; coagulation factor V/VIII-homology domains protein 1; CUB, LCCL and coagulation factor V/VIII-homology domains protein 1; discoidin CUB and LCCL domain containing 2; Discoidin, CUB and LCCL domain-containing protein 2; endothelial and smooth muscle cell-derived neuropilin-like protein; ESDN; DCBD2_HUMAN.
literatures	Specific References  (1)     |     SL5834R has been referenced in 1 publications. [IF=1.664] Zhang PF et al. MicroRNA-139 suppresses hepatocellular carcinoma cell proliferation and migration by directly targeting Topoisomerase I. ONCOLOGY LETTERS 17: 1903-1913, 2019  WB ;  Human.   PubMed:10.3892/ol.2018.9746
Research Area	Tumour  Cell biology  immunology  Cell adhesion molecule
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	78kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DCBLD2: 201-300/775 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	DCBLD2, otherwise known as ESDN (endothelial and smooth muscle cell-derived neuropilin-like molecule) is a novel type-I transmembrane protein with the longest cleavable secretory signal sequence among eukaryotes. It is expressed in various tissues; particularly highly expressed in cultured vascular smooth muscle cells. DCBLD2 is considered to play a role in regulation of vascular cell growth and may have a wide variety of functions in other tissues including the nervous system, like neuropilins. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Highly expressed in testis, heart, skeletal muscle and also in cultured vascular smooth muscle cells. Similarity: Contains 1 CUB domain. Contains 1 F5/8 type C domain. Contains 1 LCCL domain. SWISS: Q96PD2 Gene ID: 131566 Database links: Entrez Gene: 131566 Human Entrez Gene: 73379 Mouse Entrez Gene: 155696 Rat Omim: 608698 Human SwissProt: Q96PD2 Human SwissProt: Q91ZV3 Mouse SwissProt: Q91ZV2 Rat Unigene: 203691 Human Unigene: 373589 Mouse Unigene: 157411 Rat

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