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Rabbit Anti-PCDHB13 antibody
Rabbit Anti-PCDHB13 antibody
Protocadherin beta 13; PCDH BETA13; PCDHB13; PCDBD_HUMAN; Protocadherin beta-13.
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Details

Product Name PCDHB13
Chinese Name 原钙粘蛋白13抗体
Alias Protocadherin beta 13; PCDH BETA13; PCDHB13; PCDBD_HUMAN; Protocadherin beta-13.  
Research Area Tumour  Cell biology  immunology  Neurobiology  Cell adhesion molecule  Cell Surface Molecule  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Cow, Horse, Sheep, )
Applications ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 87kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human PCDHB13: 151-250/798 <Extracellular>
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008]

Function:
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein

Similarity:
Contains 6 cadherin domains.

SWISS:
Q9Y5F0

Gene ID:
56123

Database links:

Entrez Gene: 56123 Human

Omim: 606339 Human

SwissProt: Q9Y5F0 Human

Unigene: 283803 Human



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